吴学文导师主页
基本信息
姓名: 吴学文
职称: 副教授
单位电话:
电子信箱: wxw@xtu.edu.cn
办公室: 化学工程系
个人主页:
http://www.xtu.edu.cn/daoshi/?id=1700
个人简介

吴学文,男,副教授,硕士研究生导师。主持和参与科研项目多项,近年来在 Polymer Chemistry、Journal of Ethnopharmacology等国内外知名刊物上发表论文10余篇,获授权国家发明专利1项。目前研究兴趣为设计合成具生物活性的水溶性高分子纳米材料与功能调控、畅销药物中间体开发、天然产物研究与开发等。

研究方向

环境响应性高分子功能体精确构筑以及生物医药中的应用;基于现代药剂设计以及药物传输;天然产物研究与应用;医药中间体开发

科研项目

(7).主持湖南自科基金:可见光活化室温RAFT聚合构筑亲水性印迹聚合物及温敏行为(编号:2006JJ6148,2016-2018,5.0万元);

(6). 主持湘潭大学博士启动项目:RAFT聚合在医药中的应用

(5).主持省科技厅项目:齐墩果酸长循环热敏脂质体的研究(编号:2010FJ3099,2010-2011,2.0万元);

(4).主持湖南教育厅项目:pH依赖型壳聚糖衍生物合成及其在结肠给药系统中的应用(编号:07C744,2007-2009,1.0万元);

(3).参与国家自科基金:具有选择性配位和动态交换特性的聚合物胶束的设计构筑(编号:21074104 ,2010-2013,39.0万元);

(2).参与国家自科基金:希夫碱和环缩醛类光敏单体的设计合成及其可见光活化室温RAFT聚合(编号:20874081 ,2010-2013,34.0万元);

(1).参与国家自科基金:全蝎抗凝有效成分提取纯化及作用机理的研究(编号:30772715,2008-2010 27.0万);

成果获奖

吴学文,熊艳.一种阿昔洛韦醇质体及其制备方法,CN102133183A,2012.02.29已授权

代表性学术成果

[12]. Qiankun Zhu, Xiaoming Li, Yonghua Xiao, Yan Xiong*, Suiping Wang, Changli Xu, Jun Zhang, Xuewen Wu*. Synthesis of molecularly imprinted polymer via visible light activated RAFT polymerization in aqueous media at room temperature for highly selective electrochemical assay of glucose. Macromolecular Chemistry and Physics, 2017, DOI: 10.1002/macp.201700141 (proof, SCI源刊)

[11]. Yonghua Xiao, Rong Xiao, Jian Tang, Qiankun Zhu, Xiaoming Li, Yan Xiong, Xuewen Wu*. Preparation and adsorption properties of molecularly imprinted polymer via RAFT precipitation polymerization for selective removal of aristolochic acid [J]. Talanta, 2017, 162: 415-422. (SCI: 4.035)

[10]. Yan Xiong, Xuewen Wu*, Liqun Rao*. Tetrastigma hemsleyanum (Sanyeqing) root tuber extracts induces apoptosis in human cervical carcinoma HeLa cells[J]. Journal of Ethnopharmacology,2015, 165, 46–53. (Impact Factor:2.939)

[9].Xuewen Wu, Na Xu, Yuanli Cai*, Ying Zhao and Dujin Wang. Subcomponent self-assembly of polymer chains based on the dynamic and geometrical diversity of first row transition metal ions[J]. Polymer Chemistry, 2014, 5, 1202-1209. (Impact Factor :5.231)
[8].Yufang Tang, Zhilin Liu, Xuewen Wu, Guhuan Liu, Ke Yang, Yaohua Li, Lican Lu, and Yuanli Cai. Modulating Structural Stability and Acid Sensitivity of Photosensitive Polymer Micelles Simply via One-Batch UV Irradiation[J]. Journal of Polymer Science Part A: Polymer Chemistry, 2012, 50(14): 2878-2888. (Impact Factor :3.543)
[7]. Xiong, Yan, Wu Xue Wen. Comparison Studies on Antioxidant Properties of Black Sesame Seed (Sesamum indicum L.) Extracts Prepared by Thermal Processing Methods. Advanced Materials Research, 2012, 554-556: 918-921.
[6]. Yan Xiong,Liqun Rao,Li Xiong,Qiuhong Ai,Xuewen Wu*.Effects of Extraction Solvent on Polyphenolic Contents and Antioxidant Activities of Osmanthus fragrans' Seed. 2012 International Conference on Biomedical Engineering and Biotechnology. DOI:10.1109/iCBEB.2012.179.
[5]. Xuewen Wu, Yan Xiong. Effects of NaCl and pH on 2-hydroxypropyl-beta- cyclodextrin inclusion with oleanolic acid. Human Health and Biomedical Engineering (HHBE), 2011 International Conference on. DOI:10.1109/HHBE.2011.6028044.
[4]. Wu Xue Wen, Xiong, Yan. Preparation and characteristics of novelty chitosan schiff base and its zinc complexes. Advanced Materials Research, 2011, 239-242: 1364-1367.
[3].
吴学文,熊艳,蒋孟良. 不同方法制备的淡竹沥的紫外谱线组法鉴别[J]. 时珍国医国药, 2011, 22(8):1965-1966
[2].
吴学文, 熊艳, 游奎一. 樟树叶挥发性成分研究[J].广西植物2011, 31(1):139-142.
[1].
熊艳 , 吴学文. pH敏感型壳聚糖结肠定位凝胶的制备和体外释放性能[J].中国医院药学杂志, 2009, 21:1823-1826.