蔡昌群导师主页
基本信息
姓名: 蔡昌群
职称: 教授
单位电话: 15273219560
电子信箱: cai_mao3@163.com
办公室: 分析化学教研室
个人主页:
个人简介

   

蔡昌群教授博士生导师已在Analytical Chemistry,Biosensors & Bioelectronics, Analytica Chimica Acta,Sensors and actuators B-Chemical 等国际知名杂志上发表学术论文40多篇主要从事生物分析和生物传感分子印迹技术及色谱分离等方面的研究主持国家自然科学基金面上项目青年项目以及湖南省教育厅重点项目湖南省自然科学基金项目等8项科研项目

所指导研究生获奖情况

 2013级研究生杨彬获湘潭大学第21(2016研究生校长奖优秀奖

 2014级研究生陈峰获国家励志奖学金”(2016);

 2014级研究生陈峰获湘潭大学第22(2017研究生校长奖优秀奖

 2014级研究生廖溶同学获湘潭大学八一百万奖学金(2016);

 2015级研究生刘易获湘潭大学第23(2018研究生校长奖优秀奖

 2015级研究生刘易获获新宙邦奖学金和湘潭大学2016-2017年度伟人之托研究生奖学金


研究方向

生物分析与生物传感,分子印记技术以及色谱分离

科研项目

主持项目:

 

[1] 国家自然科学基金面上项目,甲型流感病毒特异性识别光化学传感器的构建及其应用研究,2018.01-2021.12,64万

[2] 国家自然科学基金青年项目,肝癌细胞DNA包封Ag 纳米簇探针的构建及无色无荧光抗癌药物体外筛选,2014.01-2016.12,25万

[3] 湖南省教育厅重点项目,基于肝炎病毒分子印迹的光化学传感器的构建及其应用研究,2016.09-2016.12,6万

[4] 湖南省自然科学基金项目:手足口病病毒特异性识别光化学传感器的构建及其应用研究,2018.01-2020.12,5万

[4] 湖南省自然科学基金项目:核酸与抗代谢类抗癌药物的反应研究及机理探讨,2011-2013,2万

[5] 湖南省教育厅:基于Fe系纳米探针高灵敏度抗代谢类抗癌药物的体外筛选,2011-2013,1万

[6] 湘潭大学科研启动项目:Fe系纳米探针在抗癌药物体外筛选中的研究与应用,2011-2014,8万

[7] 湖南省普通高等学校教学改革研究项目:改革和整合无机与分析化学实验, 培养学生的创新能力, 2012-2015, 2万

参与项目:

[1] 湖南省科技厅科技计划重点项目: 可控分子印迹纳米膜分离几种心血管手性药物的应用研究,2013-2015,15万

成果获奖

[1] 有机小分子探针及药物与核酸反应的机理研究与应用,2009,湖南省自然科学三等奖(2/4)。

   [2] 指导学生参加湖南省第八届大学生课外化学化工创新作品竞赛 获二等奖 

代表性学术成果

近3年代表性论文(第一作者或通讯作者)

(1) Liao Rong, He, Kui, Chen Chunyan, Cai Changqun*, Chen Xiaoming*, Double-strand Displacement Biosensor and Quencher-free Fluorescence Strategy for Rapid Detection of microRNA, Anal. Chem., 2016, 88, 4254-4258. IF=6.32.

(2) Yi Liu, Tian Shen, Hang Gong, Chunyan Chen, Xiaoming Chen, Changqun Cai*, An accurate and simple ratiometric fluorescence sensor for sensitive and selective detection of MicroRNA by catalyzed hairpin assembly ACsensors Doi:10.1021/acssensors.7b00313

(3) Bin Yang, Hang Gong, Chunyan Chen, Xiaoming Chen, Changqun Cai*, A virus resonance light scattering sensor based on mussel-inspired molecularly imprinted polymers for high sensitive and high selective detection of Hepatitis A Virus, Biosens. Bioelectron., 2017,87, 679. IF=7.78.

(4) Kui He, Chunyan Chen, Caishuang Liang, Bin Yang, Changqun Cai*, XiaomingChen*, Highly selective recognition and fluorescent detection of JEV by virus imprinted microspheres coating magnetic silicon. Sensor. Actuat. B-Chem., 2016,233: 607-614. IF=5.401.

(5) Feng Chen, Chunyan Chen, Xiaoming Chen, Hang Gong*, Changqun Cai*, Respective and simultaneous detection tumor markers CA125 and STIP1 for early diagnosis of ovarian cancer using aptamer-based fluorescent and RLS sensors. Sensor. Actuat B-Chem.,2017, 245:470–476. IF=5.401.

(6) Yi Liu, Tian Shen, Hang Gong, Chunyan Chen, Xiaoming Chen,Changqun Cai* , Development of a thermo-sensitive Hepatitis A virus molecularly imprinted polymers-RLS sensor and Highly Selective detection of Hepatitis A virus in vitro, Sensors and Actuators B, 2017253, 1188–1193. IF=5.401

     (7) Bin Yang, Sifang Lv, Feng Chen, Chan Liu, Changqun Cai*, Chunyan Chen, Xiaoming Chen, A resonance light scattering sensor based on bioinspired molecularly imprinted polymers for selective detection of papain at trace levels, Anal. Chim. Acta., 2016, 912:125-132. IF=4.95.

    (8) Rong Liao, shiyu Li, huan wang, Chunyan Chen, Xiaoming Chen, Changqun Cai*, Simultaneous detection of two hepatocellar carcinoma-related microRNAs using a clever single-labeled fluorescent probe, Anal. Chim. Acta.2017,983,181-188.  IF=4. 95.

(9) Feng Chen, Yi Liu, Hang Gong, Chunyan Chen, Xiaoming Chen, Changqun Cai,*Reduced graphene oxide as a resonance light-scattering probe for thrombin detection using dual-aptamer-based dsDNA, Anal. Chim. Acta.,  2017, 985, 141-147. IF=4. 95.

(10) Feng Chen, Jiaojiao Tu, Caishuang Liang, Bin Yang, Chunyan Chen, Xiaoming Chen, Changqun Cai,* Fluorescent drug screening based on aggregation of DNA-templated silver nanoclusters, and its application to iridium (III) derived anticancer drugs, Microchim. Acta., 2016, 183:1571-1577. IF=4.58.

(11) Feng Chen, Changqun Cai*, Chunyan Chen, Xiaoming Chen, “Click on the bidirectional switch”: the aptasensor for simultaneous detection of lysozyme and ATP with high sensitivity and high selectivity, Scientific Reports,2016, 6: 18814. IF=4.25.

(12) Chan Liu, Sifang Lv,Hang Gong, Chunyan Chen, Xiaoming Chen, Changqun Cai*, 2-aminopurine probe in combination with catalyzed hairpin assembly signal amplification for simple and sensitive detection of microRNA. Talanta, 2017, 174:336-340. IF=4.162.

(13) Caishuang Liang, Kui He, Huan Wang, Chunyan Chen, Xiaoming Chen and Changqun Cai*, A Virus-MIPs Fluorescent Sensor Based on FRET for Highly Sensitive Detection of JEV, Talanta, 2016,160: 360-366. IF=4.162.

(14) Sifang Lv, Feng Chen, Chunyan Chen, Xiaoming Chen, Hang Gong, Changqun Cai*, A Novel Quantum Dots Probe Amplified Resonance Light Scattering Signals for MicroRNA-122 Detection. Talanta,2017,165, 659–663. IF=4.162.

(15) Shiyu Li, Kui He, RongLiao, Chunyan Chen, Xiaoming Chen*, Hang Gong, Changqun Cai*, An interference-free and label-free sandwich-type magnetic silicon microsphere -rGO-based probe for fluorescence detection of microRNA, Talanta,2017,174, 679–683. IF=4.162.

(16) Yi Liu, Rong Liao, Huan Wang, Shiyu Li, Chunyan Chen, Xiaoming Chen, Changqun Cai*, Accurate and sensitive label-free fluorescence detection of DNA based on G-quadruplex hairpin DNA.Talanta2018,176:422-427.IF=4.162